Biotin and derivatives
Medchemexpress LLC Bis-PEG25-NHS ester | 2221948-96-3 | MFCD21363290 | 99.8% | 1413.55 | C62H112N2O33 | 50 MG
Bis-PEG25-NHS ester is a bifunctional PEG-based N-hydroxysuccinimide (NHS) ester linker used for bioconjugation, PROTAC linker assembly, and as a cleavable ADC linker. It provides a hydrophilic PEG25 spacer with two NHS reactive groups for amine coupling and conjugation chemistries.
- Bifunctional PEG25 linker with two NHS ester reactive groups.
- Purity: 99.75%.
- Molecular weight: 1413.55.
- Formula: C62H112N2O33.
- CAS number: 2221948-96-3.
- Suitable for PROTAC, ADC, and general bioconjugation applications.
- Storage: store sealed, away from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month; dry storage at -20°C.
TARGETMOL CHEMICALS INC TCO-NHS ester 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. TCO-NHS ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Purity 99.77%
Medchemexpress LLC DBCO-NHS ester 2 500mg | 1384870-47-6 | 430.45 | C25H22N2O5 | 500 MG
DBCO-NHS ester 2 is a dibenzylcyclooctyne (DBCO)-derived N-hydroxysuccinimide (NHS) ester used as an amine-reactive linker for bioconjugation and antibody-drug conjugate synthesis. The reagent enables copper-free click chemistry via strain-promoted alkyne-azide cycloaddition (SPAAC) and is supplied as a powder for laboratory use.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free click chemistry.
- Amine-reactive NHS ester for efficient labeling of proteins, peptides, and small molecules.
- Appropriate for antibody-drug conjugate (ADC) linker synthesis and general bioconjugation.
- High reported purity in product documentation.
- Powder form with long-term storage at -20°C; soluble in DMSO (≈14.29 mg/mL) with ultrasonic assistance.
Medchemexpress LLC Biotin-Val-Ala-Asp(OMe)-FMK | 1135688-15-1 | ≥95.0% | 672.81 g/mol | C30H49FN6O8S | 50 MG
Biotin-VAD-FMK is a biotin-labeled, cell-permeable, irreversible pan-caspase inhibitor used to identify and label active caspases in cell lysates. It serves as an affinity probe for detection or capture of active caspases in apoptosis research and protease-profiling workflows, and is compatible with biochemical assays and pull-down experiments.
- Biotin-labeled for affinity capture and detection.
- Cell-permeable, irreversible caspase inhibitor.
- Enables identification and labeling of active caspases in cell lysates.
- Compatible with biochemical assays, protease profiling, and pull-down workflows.
- Supplied as a solid with defined molecular weight and formula for experimental planning.
Medchemexpress LLC Biotin-Gastrin Releasing Peptide, human TFA | 3085.67 | 25 MG
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide known for its growth-stimulatory and tumorigenic properties.
- Biotinylated gastrin releasing peptide (GRP)
- Neuropeptide with growth-stimulatory properties
- Relevant for cancer and neurological disease research
- Related to GPCR/G protein and Bombesin Receptor studies
